Review Article
Year: 2021 | Month: October-December | Volume: 6 | Issue: 4 | Pages: 278-285
DOI: https://doi.org/10.52403/ijshr.20211039
Emerging Concept of Dupuytren’s Disease
Putu Feryawan Meregawa1, John Nolan2
1Departement of Orthopaedic and Traumatology, Medical Faculty, Udayana University-Sanglah General Hospital Denpasar, Indonesia
2Faculty of Medicine, Udayana University, Denpasar
Corresponding Author: Putu Feryawan Meregawa
ABSTRACT
Dupuytren’s disease is a disorder of fibroproliferative condition causing thickened and contracted of the palmar fascia. The pathophysiology behind this disease is complex and multifactorial. Some major factors are genetic predisposition, inflammatory response, trauma, comorbidities, and environmental factors. The treatment options for Dupuytren’s disease are divided into non-surgical and surgical management. Needle fasciotomy and fasciectomy are some of the most common surgical procedures chosen. Novel non-surgical treatment option as the recent advance in the treatment of the disease is the injection of collagenase Clostridium histolyticum (CCH). One of the pitfalls of Dupuytren’s management is the high possibility of the disease’s recurrence along with some other post-intervention complications. Rehabilitation following the interventions is needed to manage the maximum range of motion and curtail the inflammatory response after the cord disruption.
Keywords: Dupuytren’s disease, clostridium histolyticum, fasciectomy.