Original Research Article
Year: 2019 | Month: July-September | Volume: 4 | Issue: 3 | Pages: 199-204
Utility of Urine Cytology in Urinary Tract Neoplasm with Histopathological Correlation
Dr. D G Jaiswal1, Dr S D Dakhure2
1Associate Professor, GMC Aurangabad.
2Assistant Professor, GMC Aurangabad.
Corresponding Author: Dr S D Dakhure
ABSTRACT
Background: Urinary bladder tumor is the sixth most common tumor diagnosed worldwide. Urine cytology is an important screening tool of patients for urothelial carcinoma (UC) and follow-up of patients with treated disease. The aim of this study to determine the sensitivity of urine cytology in detection of urinary tract neoplasms with its clinical and histopathological correlation.
Material & Methods: A five years prospective study includes 73 cases of urine cytology from January 2014 to December 2018 at a tertiary care hospital in the Department of Pathology. Urine cytology slides were reviewed and were correlated with histopathological diagnosis.
Results: Out of 73 cases, histopathological follow up received only in 43 cases. Out of that, 33 were male and 10 were female. Male to female ratio is 3.3:1. Maximum age incidence was found 5th-6th decade. Hematuria was most common and presenting complaint found in 90% of cases. Urothelial carcinoma was most common neoplasm comprising for 87.5% of bladder tumors, Squamous cell carcinoma comprising 7.5%. The overall urine cytology sensitivity combining with the positive and suspicious result was 77.5%.
Conclusion: Urine cytology, despite its variable sensitivity remains a useful tool in evaluating suspected urothelial malignancies. Positive urine cytology requires confirmation with cystoscopy and biopsy before instituting any form of definitive therapy and a negative cytology does not always exclude malignant disease.
Keywords: Urothelial carcinoma, Urine cytology.