Original Research Article
Year: 2019 | Month: April-March | Volume: 4 | Issue: 2 | Pages: 20-28
Phytochemical Analysis, Antioxidant and Antibacterial Properties of Phyllanthus Emblica Leaf Extracts against Selected Bacterial Isolates
Sini. G Nath1, Dr. R. Dhivya2
1PG Student, PG and Research Department of Zoology, Nirmala College for Women, Coimbatore, Tamilnadu
2Assistant Professor, PG and Research Department of Zoology, Nirmala College for Women, Coimbatore, Tamilnadu
Corresponding Author: Dr. R. Dhivya
ABSTRACT
Background: A major challenge in global health care is the need for novel, effective and affordable medicines to treat microbial infections, as up to one-half of deaths are due to infectious diseases. The main concern is the development of antimicrobial-resistant bacteria species from a number of factors which include the prevalent and sometimes inappropriate use of antibiotics. Against this backdrop, the discovery of alternative drug classes to treat such infectious diseases is urgently required. Plants have an amazing ability to produce a wide variety of secondary metabolites which are the source of plant-derived antimicrobial substances.
Methods: Present study is carried out to investigate in vitro antibacterial activity of Phyllanthus emblica leaf extracts against the selected bacterial strains Escherichia coliand Staphylococcus aureus. Further, antioxidant activity and phytochemical analysis of the effective solvent extracts were done. Agar well diffusion was used for testing antibacterial activity. DPPH assay was carried out to evaluate antioxidant activity and phytochemical screening was tested by standard procedure.
Results: Results revealed that maximum antibacterial activity was displayed by ethanol extract of P. emblica against both the test microorganisms. Acetone extract of P. emblica embarked significant radical scavenging potential. And therefore, ethanol and acetone extract of P. emblica when analysed for the presence of phytochemicals revealed a number of phytocompounds.
Conclusion: It may be concluded that as plant extracts showed great antibacterial potential against microorganisms and revealed a rich source of antioxidant properties, they can be used as a cure for infectious diseases caused by resistant microbes.
Keywords: Antibacterial activity; Phyllanthus emblica; Plant extracts; Agar well diffusion; Antioxidant activity; DPPH Assay; Phytochemical analysis