Case Report
Year: 2018 | Month: October-December | Volume: 3 | Issue: 4 | Pages: 186-190
Plasmablastic Myeloma in a Young Patient Presenting With an Intracranial Mass Lesion - A Rare Case Report
Dr. Shipra Singhal1, Dr. Leelavathi Dawson2, Dr. Meetu Aggarwal3
1Senior Resident, 2Consultant, 3Specialist
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi (India) – 110029
Corresponding Author: Dr. Leelavathi Dawson
ABSTRACT
Plasma cell dyscrasias are a heterogeneous group of diseases which are characterized by the expansion of monoclonal plasma cells that produce monoclonal immunoglobulins. These neoplasms account for 1% of all malignant tumours. They can present as a solitary lesion (plasmacytoma) or with bone marrow involvement (multiple myeloma). The usual age of presentation of these plasma cell neoplasms is in the seventh decade. Occurrence before 30 years of age is very rare. We report a case of a 20-year-old male who presented with an intracranial space occupying lesion which was initially diagnosed as plasmacytoma and with further work up and investigations, he was finally diagnosed with plasmablastic plasma cell myeloma. In the plasma cell dyscrasia category the plasmablastic morphology is very rare. This case is being presented because of the unusual age, location, morphology, nature and sequence of presenting events.
Keywords: Multiple myeloma, Intracranial SOL, Plasmablastic myeloma, Plasmablastic lymphoma, Meningioma, Plasmacytoma